Our proprietary gene expression platform (GenetRxTM) measures drug-induced gene expression changes in small amounts of tissue, for example a single human hair or other samples such as whole blood, fractionated PBMC's, tumour and tissue biopsies, FFPE and LCM samples, sputum, lavage and CSF.  We are able to provide gene expression information from very small starting materials (as small as a single cell (10pg RNA input)), using our proprietary amplification technique.

Epistem use the GenetRx^TM technology as a means of discovering;

• Novel drug-induced biomarkers
• Preclinical and clinical gene biomarkers of efficacy (PD)
• Drug mechanisms of action at a molecular pathway level

We provide biomarker discovery services as well as qPCR assay development services.  For more information, please click here